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Table 1 Recipient, donor, and transplant characteristics

From: Timing of rabbit antithymocyte globulin induction therapy in kidney transplantation: an observational cohort study

Baseline characteristics Total (n = 477) Pre (n = 124) Post (n = 353) P value
Recipient characteristics
Mean recipient age (years) 477 48.5 ± 13.3a 51.3 ± 13.1 0.04
Recipient sex 0.14
 Male 296 70 (56.5%) 226 (64.0%)
 Female 181 54 (43.6%) 127 (36.0%)
Race     0.19
 Caucasian 289 69 (55.7%) 220 (62.3%)
 Non-Caucasian 188 55 (44.4%) 133 (37.7%)
Mean height (cm) 477 167.9 ± 11.9 168.1 ± 9.9 0.83
Mean weight (kg) 477 77.7 ± 18.1 75.1 ± 16.3 0.13
Body mass index (kg/m2) 477 27.6 ± 5.8 26.5 ± 5.2 0.07
Cause of ESRD 0.58
 Diabetes 83 17 (13.7%) 66 (18.7%)
 Glomerulonephritis 171 51 (41.1%) 120 (34.0%)
 Polycystic kidney disease 55 15 (12.1%) 40 (11.3%)
 Hypertension 48 12 (9.7%) 36 (10.2%)
 Other 120 29 (23.4%) 91 (25.8%)
Transplant number 0.57
First graft 396 105 (84.7%) 291 (82.4%)
Re-graft 81 19 (15.3%) 62 (17.6%)
Median PRA (%)b 477 15 (0,49) 10 (0,46) 0.23
Median length of stay (days)b 477 9 (7,12) 11 (8,16) 0.01
Donor characteristics
Mean donor age (years) 477 45.8 ± 13.9 48.5 ± 14.2 0.05
Donor sex 1.00
 Male 250 65 (52.4%) 185 (52.4%)
 Female 227 59 (47.8%) 168 (47.6%)
Median donor CrCl (mL/min)b, c 445 (117/328)d 110.6 (92.9, 137.6) 110.5 (91.5, 140.9) 0.88
Mean CIT (min)e 244 (38/206)d 954.7 ± 314.7 810.7 ± 375.2 0.03
Donor type (%) 0.002
 Deceased 312 67 (54.0%) 245 (69.4%)
 Living 165 57 (46.0%) 108 (30.6%)
DCD kidneys  
 No 443 124 (100%) 319 (90.4%) <0.001
 Yes 34 0 (0%) 34 (9.6%)  
Transplant characteristics
Transplant era (%)     <0.001
 2002 to 2004 86 31 (25.0%) 55 (15.6%)
 2005 to 2007 186 61 (49.2%) 125 (35.4%)
 2008 to 2009 205 32 (25.8%) 173 (49.0%)
Delayed graft function     
 No 332 99 (79.8%) 233 (66.0%) 0.004
 Yes 145 25 (20.2%) 120 (34.0%)  
Maintenance CNI <0.001
 Tacrolimus 360 78 (62.9%) 282 (79.9%)
 Cyclosporine 106 45 (36.3%) 61 (17.3%)
 CNI-free 11 1 (0.8%) 10 (2.8%)
  1. CIT, cold ischemia time; CNI, calcineurin inhibitor; CrCl, creatinine clearance; DCD, donation after cardiac death; ESRD, end stage renal disease; PRA, panel reactive antibodies.
  2. aPlus-minus values are means ± standard deviation.
  3. bMedian (interquartile range).
  4. cCreatinine clearance estimated using the Cockcroft-Gault formula.
  5. dTotal number assessed (Pre group/Post group).
  6. eDeceased donor kidney transplants only.
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