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Table 1 Recipient, donor, and transplant characteristics

From: Timing of rabbit antithymocyte globulin induction therapy in kidney transplantation: an observational cohort study

Baseline characteristics

Total (n = 477)

Pre (n = 124)

Post (n = 353)

P value

Recipient characteristics

Mean recipient age (years)

477

48.5 ± 13.3a

51.3 ± 13.1

0.04

Recipient sex

0.14

 Male

296

70 (56.5%)

226 (64.0%)

 Female

181

54 (43.6%)

127 (36.0%)

Race

   

0.19

 Caucasian

289

69 (55.7%)

220 (62.3%)

 Non-Caucasian

188

55 (44.4%)

133 (37.7%)

Mean height (cm)

477

167.9 ± 11.9

168.1 ± 9.9

0.83

Mean weight (kg)

477

77.7 ± 18.1

75.1 ± 16.3

0.13

Body mass index (kg/m2)

477

27.6 ± 5.8

26.5 ± 5.2

0.07

Cause of ESRD

0.58

 Diabetes

83

17 (13.7%)

66 (18.7%)

 Glomerulonephritis

171

51 (41.1%)

120 (34.0%)

 Polycystic kidney disease

55

15 (12.1%)

40 (11.3%)

 Hypertension

48

12 (9.7%)

36 (10.2%)

 Other

120

29 (23.4%)

91 (25.8%)

Transplant number

0.57

First graft

396

105 (84.7%)

291 (82.4%)

Re-graft

81

19 (15.3%)

62 (17.6%)

Median PRA (%)b

477

15 (0,49)

10 (0,46)

0.23

Median length of stay (days)b

477

9 (7,12)

11 (8,16)

0.01

Donor characteristics

Mean donor age (years)

477

45.8 ± 13.9

48.5 ± 14.2

0.05

Donor sex

1.00

 Male

250

65 (52.4%)

185 (52.4%)

 Female

227

59 (47.8%)

168 (47.6%)

Median donor CrCl (mL/min)b, c

445 (117/328)d

110.6 (92.9, 137.6)

110.5 (91.5, 140.9)

0.88

Mean CIT (min)e

244 (38/206)d

954.7 ± 314.7

810.7 ± 375.2

0.03

Donor type (%)

0.002

 Deceased

312

67 (54.0%)

245 (69.4%)

 Living

165

57 (46.0%)

108 (30.6%)

DCD kidneys

 

 No

443

124 (100%)

319 (90.4%)

<0.001

 Yes

34

0 (0%)

34 (9.6%)

 

Transplant characteristics

Transplant era (%)

   

<0.001

 2002 to 2004

86

31 (25.0%)

55 (15.6%)

 2005 to 2007

186

61 (49.2%)

125 (35.4%)

 2008 to 2009

205

32 (25.8%)

173 (49.0%)

Delayed graft function

    

 No

332

99 (79.8%)

233 (66.0%)

0.004

 Yes

145

25 (20.2%)

120 (34.0%)

 

Maintenance CNI

<0.001

 Tacrolimus

360

78 (62.9%)

282 (79.9%)

 Cyclosporine

106

45 (36.3%)

61 (17.3%)

 CNI-free

11

1 (0.8%)

10 (2.8%)

  1. CIT, cold ischemia time; CNI, calcineurin inhibitor; CrCl, creatinine clearance; DCD, donation after cardiac death; ESRD, end stage renal disease; PRA, panel reactive antibodies.
  2. aPlus-minus values are means ± standard deviation.
  3. bMedian (interquartile range).
  4. cCreatinine clearance estimated using the Cockcroft-Gault formula.
  5. dTotal number assessed (Pre group/Post group).
  6. eDeceased donor kidney transplants only.
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Transplantation Research

ISSN: 2047-1440

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