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  1. Content type: Research

    The aim of this study is to determine the feasibility of using nuclear magnetic resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissu...

    Authors: Jay Nath, Tom Smith, Alex Hollis, Sam Ebbs, Sefa W. Canbilen, Daniel A. Tennant, Andrew R. Ready and Christian Ludwig

    Citation: Transplantation Research 2016 5:7

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  2. Content type: Research

    Post-transplant lymphoproliferative disorder (PTLD) adversely affects patients’ long-term outcome.

    Authors: Lisa Rausch, Christian Koenecke, Hans-Friedrich Koch, Alexander Kaltenborn, Nikos Emmanouilidis, Lars Pape, Frank Lehner, Viktor Arelin, Ulrich Baumann and Harald Schrem

    Citation: Transplantation Research 2016 5:6

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  3. Content type: Research

    Over the past three decades, public attitudes to organ donation have been a subject of numerous studies focusing on donor motivation. Here, we present a fresh approach. We suggest focusing on public acceptabil...

    Authors: Francisca Nordfalk, Maria Olejaz, Anja M. B. Jensen, Lea Larsen Skovgaard and Klaus Hoeyer

    Citation: Transplantation Research 2016 5:5

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  4. Content type: Clinical trial protocol

    Ischaemic reperfusion (IR) injury is a major cause of graft loss, morbidity and mortality following orthotopic liver transplantation (OLT). Demand for liver transplantation has resulted in increasing use of ma...

    Authors: Francis P. Robertson, Rup Goswami, Graham P. Wright, Barry Fuller and Brian R. Davidson

    Citation: Transplantation Research 2016 5:4

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  5. Content type: Clinical trial protocol

    Tacrolimus is available as twice-daily Prograf® (Tac-BID) and the once-daily formulation, Advagraf® (Tac-OD). Although therapeutically equivalent, some transplant recipients require dose adjustments to achieve...

    Authors: Alina S. R Zaltzman, Lauren A. Glick, Jeffrey S. Zaltzman, Michelle Nash, Michael Huang and G. V. Ramesh Prasad

    Citation: Transplantation Research 2016 5:2

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  6. Content type: Research

    Silibinin has been shown to have anti-HCV activity and immune-modulating properties by regulating dendritic cell (DC) function. DCs are antigen-presenting cells that, together with regulatory T cells (Treg), p...

    Authors: Antonino Castellaneta, Antonio Massaro, Maria Rendina, Francesca D’Errico, Sonia Carparelli, Salvatore Fabio Rizzi, Angus W. Thomson and Alfredo Di Leo

    Citation: Transplantation Research 2016 5:1

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  7. Content type: Review

    Here, we review 15 years of clinical use of sirolimus in our transplant center, in context with the developing immunosuppressive strategies use worldwide. The majority of studies were conducted in de novo kidn...

    Authors: Helio Tedesco Silva Jr, Claudia Rosso Felipe and Jose Osmar Medina Pestana

    Citation: Transplantation Research 2015 4(Suppl 1):28

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    This article is part of a Supplement: Volume 4 Supplement 1

  8. Content type: Review

    Immunosuppressive therapy after kidney transplantation is based on calcineurin inhibitors (CNI). In most cases CNI therapy is combined with mycophenolate and steroids. In spite of good short-term results this ...

    Authors: Fritz Diekmann and Josep M. Campistol

    Citation: Transplantation Research 2015 4(Suppl 1):29

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    This article is part of a Supplement: Volume 4 Supplement 1

  9. Content type: Research

    Determining eligibility for a kidney transplant is an important decision. Practice guidelines define contraindications to transplantation; however many are not evidence based. Canadian guidelines recommend tha...

    Authors: Bryce A. Kiberd, Meteb M AlBugami, Romuald Panek and Karthik Tennankore

    Citation: Transplantation Research 2015 4:2

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  10. Content type: Research

    The effects of pre-transplantation medication for secondary hyperparathyroidism on post-transplantation parathyroid hormone (PTH) and calcium levels have not yet been conclusively determined. Therefore, this s...

    Authors: Frank-Peter Tillmann, Carolin Wächtler, Anita Hansen, Lars Christian Rump and Ivo Quack

    Citation: Transplantation Research 2014 3:21

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  11. Content type: Research

    Premature cardiovascular (CV) death is the commonest cause of death in renal transplant recipients. Abnormalities of left ventricular (LV) structure (collectively termed uremic cardiomyopathy) and left atrial ...

    Authors: Rajan K Patel, Christopher Pennington, Kathryn K Stevens, Alison Taylor, Keith Gillis, Elaine Rutherford, Nicola Johnston, Alan G Jardine and Patrick B Mark

    Citation: Transplantation Research 2014 3:20

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  12. Content type: Research

    Primary graft dysfunction (PGD) is a significant cause of early morbidity and mortality following lung transplantation. Improved organ preservation techniques will decrease ischemia-reperfusion injury (IRI) co...

    Authors: Saverio La Francesca, Anthony E Ting, Jason Sakamoto, Jessica Rhudy, Nicholas R Bonenfant, Zachary D Borg, Fernanda F Cruz, Meagan Goodwin, Nicholas A Lehman, Jennifer M Taggart, Robert Deans and Daniel J Weiss

    Citation: Transplantation Research 2014 3:19

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  13. Content type: Research

    The failure of a kidney transplant is now a common reason for initiation of dialysis therapy. Kidney transplant recipients commencing dialysis have greater morbidity and mortality than transplant-naïve, incide...

    Authors: Jennifer A McCaughan, Christopher C Patterson, Alexander P Maxwell and Aisling E Courtney

    Citation: Transplantation Research 2014 3:18

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  14. Content type: Research

    ABO-incompatible live donor liver transplant (ABOi-LDLT) is being widely done to bridge the gap of demand and supply of organs. Different desensitization regimes are being used to reduce titer of blood group a...

    Authors: Aseem Kumar Tiwari, Prashant Pandey, Geet Aggarwal, Ravi C Dara, Ganesh Rawat, Vimarsh Raina and Arvinder Singh Soin

    Citation: Transplantation Research 2014 3:17

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  15. Content type: Research

    Delayed graft function (DGF) remains a significant and detrimental postoperative phenomenon following living-related renal allograft transplantation, with a published incidence of up to 15%. Early therapeutic ...

    Authors: Stephen J Goodyear, James Barnes, Caitlin E Imray, Robert Higgins, For T Lam, S Habib Kashi, Lam C Tan and Christopher HE Imray

    Citation: Transplantation Research 2014 3:16

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  16. Content type: Commentary

    Patients with renal transplant are at higher risk of mortality from cardiovascular disease (CVD) compared with the general population. Physical activity has been shown to reduce the risk of CVD mortality in th...

    Authors: Dorothy Wei Yun Wang, Laura L Sills, Sara B MacDonald, Ziv Maianski and Ian Alwayn

    Citation: Transplantation Research 2014 3:15

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  17. Content type: Research

    The purpose of this study was to test the efficacy and safety of daclizumab (DZM) versus anti-thymocyte globulin (ATG) as a component of induction therapy in heart transplant recipients.

    Authors: John C Mullen, Emily J Kuurstra, Antigone Oreopoulos, Michael J Bentley and Shaohua Wang

    Citation: Transplantation Research 2014 3:14

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  18. Content type: Research

    Extracorporeal membranous oxygenation is proposed for abdominal organ procurement from donation after circulatory determination of death (DCD). In France, the national Agency of Biomedicine supervises the proc...

    Authors: Géraldine Allain, Thomas Kerforne, Rodolphe Thuret, Pierre-Olivier Delpech, Thibaut Saint-Yves, Michel Pinsard, Thierry Hauet, Sébastien Giraud, Christophe Jayle and Benoît Barrou

    Citation: Transplantation Research 2014 3:13

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  19. Content type: Clinical trial protocol

    Corticosteroids and calcineurin inhibitors (CNIs) are included in renal transplantation immunosuppressive protocols around the world. Well-known side effects are associated with the use of these drugs, includi...

    Authors: Jana Ekberg, Henrik Ekberg, Bente Jespersen, Ragnar Källen, Karin Skov, Michael Olausson, Lars Mjörnstedt and Per Lindnér

    Citation: Transplantation Research 2014 3:12

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  20. Content type: Research

    Bronchoscopy represents an important diagnostic and therapeutic tool in the management of lung transplant (LTx) recipients. Outpatient bronchoscopy reduces health costs and may improve quality of life amongst ...

    Authors: Jessica Rademacher, Hendrik Suhling, Mark Greer, Axel Haverich, Tobias Welte, Gregor Warnecke and Jens Gottlieb

    Citation: Transplantation Research 2014 3:11

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  21. Content type: Review

    Cutaneous melanoma carries the potential for substantial morbidity and mortality in the solid organ transplant population. We systematically reviewed the literature published from January 1995 to January 2012 ...

    Authors: Erin Dahlke, Christian Alexander Murray, Jessica Kitchen and An-Wen Chan

    Citation: Transplantation Research 2014 3:10

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  22. Content type: Research

    The Swiss organ allocation system for donor lungs was implemented on 1 July 2007. The effects of this implementation on patient selection, intensive care unit course, outcomes and intensive care costs are unkn...

    Authors: Stephanie Klinzing, Giovanna Brandi, Dimitri A Raptis, Urs Wenger, Denise Weber, Paul A Stehberger, Ilhan Inci and Markus Béchir

    Citation: Transplantation Research 2014 3:9

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  23. Content type: Review

    In countries where presumed consent for organ donation does not apply, health professionals (HP) are key players for identifying donors and obtaining their consent. This systematic review was designed to verif...

    Authors: Frédéric Douville, Gaston Godin and Lydi-Anne Vézina-Im

    Citation: Transplantation Research 2014 3:8

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  24. Content type: Research

    Tacrolimus is a widely used calcineurin inhibitor in kidney transplantation. It is available as twice-daily Prograf® (Tac-BID) and once-daily Advagraf® (Tac-OD). Although therapeutically equivalent, some patie...

    Authors: Lauren Glick, Fernanda Shamy, Michelle Nash, Ahmed Sokwala, Tushar Malavade, GV Ramesh Prasad and Jeffrey S Zaltzman

    Citation: Transplantation Research 2014 3:7

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  25. Content type: Research

    The volume and outcome relationship for transplant procedures has become one of the major topics during discussions about consequences following the organ transplantation scandal of wait-list manipulations in ...

    Authors: Annemarie Nijboer, Frank Ulrich, Wolf O Bechstein and Andreas A Schnitzbauer

    Citation: Transplantation Research 2014 3:5

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  26. Content type: Reviewer Acknowledgement

    The Editors of Transplantation Research would like to thank all our reviewers who have contributed to the journal in Volume 2 (2013).

    Authors: Edward K Geissler and Alan Jardine

    Citation: Transplantation Research 2014 3:3

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  27. Content type: Research

    We analyzed all PRA-negative patients who received a first kidney transplant from an HLA-identical living donor. The patients received no antibody induction. An intraoperative bolus of 500 mg of methylpredniso...

    Authors: Blanca Gascó, Ignacio Revuelta, Ana Sánchez-Escuredo, Miquel Blasco, Federico Cofán, Nuria Esforzado, Luis F Quintana, María José Ricart, José Vicente Torregrosa, Josep M Campistol, Federico Oppenheimer and Fritz Diekmann

    Citation: Transplantation Research 2014 3:4

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  28. Content type: Research

    Literature on the timing of rabbit antithymocyte globulin (rATG) induction and its effects on kidney transplant outcomes is limited. The manufacturer recommends that the first dose be given intra-operatively, ...

    Authors: Jennifer J Harrison, Bassem Hamandi, Yanhong Li, Olusegun Famure and S Joseph Kim

    Citation: Transplantation Research 2014 3:1

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  29. Content type: Review

    Mammalian target of rapamycin (mTOR) inhibitors are currently considered an alternative immunosuppressive treatment that can prevent the nephrotoxicity, viral infections and malignancies that are associated wi...

    Authors: Philippe Gatault and Yvon Lebranchu

    Citation: Transplantation Research 2013 2(Suppl 1):S3

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    This article is part of a Supplement: Volume 2 Supplement 1

  30. Content type: Review

    JAK3 inhibition with the CP-690,550 compound has an immunosuppressive potency in murine models, nonhuman primates and humans. This drug blocks STAT5 activation in most T-cell subpopulations but less effectivel...

    Authors: Christophe Legendre

    Citation: Transplantation Research 2013 2(Suppl 1):S6

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    This article is part of a Supplement: Volume 2 Supplement 1

  31. Content type: Review

    The known role of mammalian target of rapamycin (mTOR) in the immune response has been rapidly evolving, from what was once thought to be a simple immunosuppressive antiproliferative effect on T cells to a ver...

    Authors: Edward K Geissler

    Citation: Transplantation Research 2013 2(Suppl 1):S2

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    This article is part of a Supplement: Volume 2 Supplement 1

  32. Content type: Research

    Renal transplant candidates are at high risk of coronary artery disease (CAD). We sought to develop a new risk score model to determine the pre-test probability of the occurrence of significant CAD in renal tr...

    Authors: Luís Henrique Wolff Gowdak, Flávio Jota de Paula, Luiz Antônio Machado César, Luiz Aparecido Bortolotto and José Jayme Galvão de Lima

    Citation: Transplantation Research 2013 2:18

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  33. Content type: Research

    Immune monitoring by flow cytometry is a fast and highly informative way of studying the effects of novel therapeutics aimed at reducing transplant rejection or treating autoimmune diseases. The ONE Study cons...

    Authors: Mathias Streitz, Tewfik Miloud, Michael Kapinsky, Michael R Reed, Robert Magari, Edward K Geissler, James A Hutchinson, Katrin Vogt, Stephan Schlickeiser, Anders Handrup Kverneland, Christian Meisel, Hans-Dieter Volk and Birgit Sawitzki

    Citation: Transplantation Research 2013 2:17

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  34. Content type: Research

    Allograft fibrosis still remains a critical problem in transplantation, including heart transplantation. The IL-13/TGF-β1 interaction has previously been identified as a key pathway orchestrating fibrosis in diff...

    Authors: Stefan M Brunner, Gabriela Schiechl, Rebecca Kesselring, Maria Martin, Saidou Balam, Hans J Schlitt, Edward K Geissler and Stefan Fichtner-Feigl

    Citation: Transplantation Research 2013 2:16

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  35. Content type: Research

    Kidney transplant recipients are recognized as a vulnerable population that is at increased risk of adverse health outcomes. However, there have been few studies that have compared hospital-related morbidity o...

    Authors: Ying Jiang, Paul J Villeneuve, Douglas Schaubel, Yang Mao, Panduranga Rao and Howard Morrison

    Citation: Transplantation Research 2013 2:15

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  36. Content type: Research

    No study to date has evaluated the efficacy and safety of everolimus with reduced-exposure cyclosporine in Japanese de-novo renal transplant (RTx) patients.

    Authors: Kota Takahashi, Kazuharu Uchida, Norio Yoshimura, Shiro Takahara, Satoshi Teraoka, Rie Teshima, Catherine Cornu-Artis and Eiji Kobayashi

    Citation: Transplantation Research 2013 2:14

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  37. Content type: Research

    The first crucial step in transplantation appears to be the effective rinsing of the graft during organ procurement. Even though there is strong suspicion that ex situ perfusion results in better rinsing of the g...

    Authors: Daniel Foltys, Moritz Kaths, Mari Strempel, Uwe Scheuermann, Axel Heimann, Veronika Weyer, Torsten Hansen, Oliver Kempski and Gerd Otto

    Citation: Transplantation Research 2013 2:13

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  38. Content type: Clinical trial protocol

    Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenil...

    Authors: Andrea Proneth, Andreas A Schnitzbauer, Florian Zeman, Johanna R Foerster, Ines Holub, Helmut Arbogast, Wolf O Bechstein, Thomas Becker, Carsten Dietz, Markus Guba, Michael Heise, Sven Jonas, Stephan Kersting, Jürgen Klempnauer, Steffen Manekeller, Volker Müller…

    Citation: Transplantation Research 2013 2:12

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  39. Content type: Research

    The most important limiting factor in kidney transplantation is the scarcity of donor organs. Consequently, there is an increased use worldwide of kidneys from older deceased donors. High donor age is a known ...

    Authors: Kristian Heldal, Solveig Thorarinsdottir, Anders Hartmann, Torbjørn Leivestad, Anna V Reisæter, Aksel Espen Foss and Karsten Midtvedt

    Citation: Transplantation Research 2013 2:11

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