| |
Univariable
|
Multivariable model 1
|
Multivariable model 2
|
|---|
| |
HR
|
95% CI
|
P
|
HR
|
95% CI
|
P
|
HR
|
95% CI
|
P
|
|---|
|
Delayed graft function
|
5.21
|
2.17 to 12.48
|
< 0.001
|
5.04
|
2.05 to 12.42
|
< 0.001
|
5.41
|
2.20 to 13.34
|
< 0.001
|
|
IL-2 minus
|
4.13
|
1.78 to 9.57
|
0.001
|
4.59
|
1.91 to 11.02
|
0.001
|
3.81
|
1.53 to 9.49
|
0.004
|
|
Time on dialysis (per year)
|
1.23
|
0.94 to 1.63
|
0.1
|
1.20
|
0.89 to 1.62
|
ns
|
1.22
|
0.91 to 1.63
|
ns
|
|
Recipient gender
|
1.72
|
0.65 to 4.58
|
0.3
|
1.26
|
0.46 to 3.43
|
ns
|
1.23
|
0.45 to 3.34
|
ns
|
|
Recipient age
|
1.01
|
0.98 to 1.05
|
0.5
|
1.00
|
0.97 to 1.03
|
ns
|
1.00
|
0.97 to 1.04
|
ns
|
|
Steroid-resistant rejection
|
3.65
|
1.52 to 8.74
|
0.004
| | | |
2.52
|
1.01 to 6.29
|
0.05
|
- N = 232; 25 graft loss, no missing variables.
- The following variables were tested in the univariable model but not included in the multivariable model: CMV-positive donor, CMV-positive recipient, presence of HLA antibodies, donor age, donor gender, any HLA-A, HLA-B or HLA-DR mismatch, type of calcineurin inhibitor (tacrolimus versus CsA), cold ischemia time and presence of acute rejection episodes 90 or 180 days after transplantation.
