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Table 2 Up-regulated proteins a in AR/control urine samples compared to baseline shown for individual patients

From: Urinary proteomic shotgun approach for identification of potential acute rejection biomarkers in renal transplant recipients

   

Rejection group

No-rejection group

   

AR 1

AR 2

AR 3

AR 4

AR 5

AR 6

C 1

C 2

C 3

C 4

C 5

C 6

  

Banff classification

I3T1V0 C4d-

I2T2V0 C4d-

I2T2V0 C4d-

I2T2V0 C4d-

I2T3V0 C4d-

I3T1V2 C4d-

NA

NA

NA

NA

NA

NA

IPI ID

Gene ID

Protein name

Log 2 change

Log 2 change

Immune proteins

             

IPI00217775.1

CD74

Isoform 2 of HLA class II histocompatibility antigen gamma chain

NDb

0.47

2.57

4.06

1.81

1.23

0.39

1.03

0.81

0.99

2.10

0.58

IPI00004573.2

PIGR

Polymeric immunoglobulin receptor

−0.04

0.66

2.27

1.31

0.36

2.20

0.29

0.63

0.71

1.65

0.19

0.14

IPI00783987.2

C3

Complement C3 (Fragment)

−0.17

3.17

−0.48

1.25

−5.32

2.64

−3.49

ND

1.14

−4.80

−1.54

−3.63

IPI00017601.1

CP

Ceruloplasmin

0.42

4.40

0.34

1.15

ND

4.79

−1.87

−1.25

0.22

−1.02

0.53

−2.02

IPI00306378.5

MASP2

Isoform 2 of Mannan-binding lectin serine protease 2

1.10

1.88

1.36

2.30

1.26

4.06

0.57

−3.94

1.94

1.19

2.44

0.43

IPI00011302.1

CD59

CD59 glycoprotein

−2.65

1.16

1.30

1.74

0.40

3.62

−1.52

2.68

−1.90

1.73

1.31

0.19

Growth factors

             

IPI00016915.1

IGFBP7

Insulin-like growth factor-binding protein 7

0.11

−0.43

2.40

1.01

−0.91

2.84

0.71

1.42

0.05

0.58

−0.02

ND

IPI00966866.1

EGF

Epidermal growth factor

1.71

3.49

2.15

0.75

0.97

ND

0.79

ND

ND

1.51

0.51

0.13

IPI00395488.2

VASN

Vasorin

1.27

1.11

ND

0.61

0.05

2.10

0.96

−2.27

2.00

0.66

1.69

−0.81

IPI00023673.1

LGALS3BP

Galectin-3-binding protein

1.01

0.20

2.62

1.76

0.61

3.59

0.26

1.21

0.03

1.15

0.32

0.30

Other

              

IPI00004372.3

MEP1A

MEP1A protein (Meprin A subunit alpha)

ND

ND

1.87

2.87

1.31

1.02

ND

ND

ND

ND

ND

ND

  1. a Criteria for up-regulation: up-regulation (log 2 change ≥1) from baseline to AR in at least three patients in the AR-group. Proteins with higher average ratio in the control group and proteins more frequently up-regulated in the control group were excluded. b ND: Not detected.
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Transplantation Research

ISSN: 2047-1440

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