Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation

Table 1 Mouse vs. human immature RAPA-DC

	Mouse	Human
Phenotype[19, 23, 26, 27]
MHC Class II	↓	-
CD86/ CD40	↓↓	↓
B7-H1	↓	↓
Migration[10, 23, 24]
CCR7	-	↑
Treg[21–23]
enrichment/induction/expansion	↑	↑
T cell apoptosis[10]	↑	ND
Function[15, 19, 20, 23, 27–29]
Endocytosis	↓↓	ND
MLR	↓↓	↓
IL-12p70	↓	-
IL-10	↓	-

ISSN: 2047-1440