Variable | PTLD mean | Non-PTLD mean | Mean difference of Non-PTLD minus PTLD | p valuea | Standard error of mean difference |
---|---|---|---|---|---|
Survival after Tx in years | 7.74 | 9.98 | 2.24 | 0.004 | 0.72 |
PTLD-free survival in years | 3.99 | 9.98 | 5.99 | <0.001 | 0.76 |
Number of subsequent re-transplants | 0.17 | 0.17 | 0.00 | 1.000 | 0.10 |
CIT in minutes | 658.07 | 627.07 | −31.00 | 0.756 | 99.05 |
BMI in kg/m2 | 20.05 | 20.13 | 0.09 | 0.890 | 0.62 |
Number of episodes of graft rejection | 0.71 | 1.17 | 0.46 | 0.118 | 0.29 |
Number of episodes of EBV de novo infections or reactivations | 0.50 | 0.50 | 0.00 | 1.000 | 0.15 |
Number of episodes of CMV de novo infections or reactivations | 1.47 | 0.75 | −0.72 | 0.042 | 0.34 |
Duration of pre-Tx dialysis in years | 4.02 | 4.65 | 0.63 | 0.561 | 1.06 |
Number of HLA A locus recipient-donor mismatches | 0.76 | 0.71 | −0.06 | 0.791 | 0.22 |
Number of HLA B locus recipient-donor mismatches | 1.12 | 1.06 | −0.06 | 0.805 | 0.23 |
Number of HLA DR locus recipient-donor mismatches | 0.94 | 1.06 | 0.12 | 0.431 | 0.15 |
Overall number of HLA recipient-donor mismatches | 2.82 | 2.82 | 0.00 | 1.000 | 0.51 |
Daily dose of tacrolimus in mgb after Tx | 3.74 | 1.62 | −2.12 | 0.052 | 1.05 |
Blood level of tacrolimus in ng/mlb after Tx | 9.97 | 8.13 | −1.83 | 0.734 | 4.69 |
Daily dose of ciclosporine in mgb after Tx | 176.17 | 183.06 | 6.89 | 0.832 | 32.24 |
C0 blood level of ciclosporine in μg/lb after Tx | 218.46 | 195.91 | −22.55 | 0.230 | 17.63 |
C2 blood level of ciclosporine in μg/lb after Tx | 1183.0 | 1168.5 | −14.5 | 0.909 | 100.5 |
Daily dose of MMF in mg afterb after Tx | 545.00 | 551.67 | 6.67 | 0.967 | 161.43 |
Daily dose of prednisolone in mgb after Tx | 11.13 | 10.99 | −0.14 | 0.916 | 1.31 |
Daily dose of sirolimus inb after Tx | 0.06 | 0.06 | 0.00 | 1.000 | 0.08 |
Daily dose of everolimus in mgb after Tx | 0.06 | 0.14 | 0.08 | 0.585 | 0.15 |
Daily dose of azathioprine in mgb after Tx | 2.08 | 2.78 | 0.69 | 0.160 | 0.48 |
Tacrolimus treatment in months c | 12.47 | 15.62 | 3.15 | 0.596 | 5.87 |
Tacrolimus treatment in % of time of immunosuppressionc | 46.87 | 33.45 | −13.42 | 0.231 | 11.00 |
Ciclosporine treatment in monthsc | 27.16 | 25.58 | −1.58 | 0.737 | 4.67 |
Ciclosporine treatment in % of time of immunosuppressionc | 46.25 | 59.70 | 13.45 | 0.180 | 9.83 |
CNI-free treatment in monthsc | 6.96 | 5.29 | −1.67 | 0.628 | 3.41 |
CNI-free treatment in % of time of immunosuppressionc | 7.81 | 6.69 | −1.11 | 0.803 | 4.42 |