Table 1 Demographic, clinical and drug data for patients at pre-transplant cardiac assessment
Variable | Total N = 119 | Alive N = 96 | Dead N = 23 | p |
|---|---|---|---|---|
Age at CMR (years) | 50.5 (±10.2) | 49.8 (±9.7) | 53.7 (±11.5) | 0.05* |
Male (%) | 83 (69.7) | 71 (74.0) | 12 (52.2) | 0.04* |
BSA (m2) | 1.84 (±0.3) | 1.86 (±0.3) | 1.77 (±0.2) | 0.12 |
BMI (kg/m2) | 25.0 (±4.7) | 24.9 (±0.7) | 25.4 (±4.5) | 0.12 |
Systolic BP (mmHg) | 138 (±23) | 137 (±23) | 141 (±24.2) | 0.38 |
Diastolic BP (mmHg) | 82 (±12.7) | 82 (±13) | 81 (±13) | 0.77 |
RRT time to CMR (years) | 2.2 (0.6, 5.2) | 1.7 (0.7, 3.9) | 2.5 (0.6, 5.8) | 0.57 |
RRT | ||||
HD | 100 (84.0) | 84 (87.5) | 16 (69.5) | 0.91 |
PD | 19 (16.0) | 11 (11.4) | 8 (34.7) | |
Diabetes mellitus | 73 (61.3) | 61 (63.5) | 12 (52.2) | 0.32 |
Ischemic heart disease | 17 (14.3) | 13 (13.5) | 4 (17.4) | 0.64 |
Heart failure | 6 (5.0) | 5 (5.2) | 1 (4.3) | 0.86 |
Cerebrovascular disease | 12 (10.1) | 6 (6.3) | 6 (26.1) | 0.005* |
Peripheral vascular disease | 7 (5.9) | 4 (4.2) | 3 (13.0) | 0.10 |
Dyslipidemia | 34 (28.6) | 26 (27.1) | 8 (34.8) | 0.46 |
Smoking | ||||
Never | 52 (43.7) | 44 (45.8) | 8 (34.8) | 0.14 |
Current/Ex smoker | 67 (56.3) | 52 (54.2) | 15 (65.2) | |
Epo receptor agonist | 92 (77.3) | 74 (77.9) | 18 (78.3) | 0.97 |
β adrenoceptor blocker | 40 (33.6) | 35 (37.6) | 5 (21.7) | 0.15 |
Aspirin | 32 (26.9) | 26 (28.0) | 6 (26.1) | 0.86 |
Warfarin | 5 (4.2) | 2 (2.2) | 3 (13.0) | 0.08 |
ACEI/ARB pre-transplant | 25 (21.0) | 22 (23.4) | 3 (13.0) | 0.28 |
Diuretic | 30 (25.2) | 24 (25.8) | 6 (26.1) | 0.98 |
Calcium channel blocker | 29 (24.4) | 23 (24.7) | 6 (26.1) | 0.89 |
α adrenoceptor blocker | 10 (8.4) | 9 (9.7) | 1 (4.3) | 0.42 |
Statin | 34 (28.6) | 26 (28.0) | 8 (34.8) | 0.52 |
Hemoglobin (g/l) | 117 (±17) | 117 (±1.7) | 117 (±1.8) | 0.97 |
CRP | 6.0 (4.0, 41.2) | 6.0 (4.0, 12.0) | 19 (4.0, 49.5) | 0.19 |
Corrected calcium (mmol/l) | 2.42 (±0.4) | 2.41 (±0.4) | 2.42 (±0.5) | 0.97 |
Phosphate (mmol/l) | 1.67 (±0.4) | 1.71 (±0.4) | 1.52 (±0.5) | 0.30 |
Albumin (g/l) | 41.5 (±4.3) | 42.5 (±3.7) | 37.5 (±4.7) | 0.008* |
Ejection fraction (%) | 66.3 (±10.2) | 66.3 (±9.5) | 66.4 (±12.3) | 0.99 |
LVSD on MRI (EF < 55%) | 16 (13.4) | 11 (11.5) | 5 (21.7) | 0.19 |
Myocardial mass/BSA (g/m2) | 96.4 (±31.7) | 95.2 (±31.7) | 101.6 (±32.4) | 0.38 |
LVH | 78 (65.5) | 58 (60.4) | 20 (87.0) | 0.16 |
ESV/BSA (ml/m2) | 25.1 (±14.8) | 72.4 (±25.7) | 73.5 (±25.2) | 0.85 |
EDV/BSA (ml/m2) | 72.7 (±25.5) | 24.9 (±13.8) | 25.9 (±18.9) | 0.77 |
LV dilation | 14 (13.4) | 11 (11.5) | 3 (13.0) | 0.83 |
LA volume/BSA (ml/m2) | 32.1 (±7.7) | 31.0 (±6.7) | 36.4 (±9.1) | 0.01* |