| ATG (n = 15) | DZM (n = 15) | p value |
---|---|---|---|
Average white blood cells (×109/L) | 16.6 ± 1.3 | 16.4 ± 1.2 | 0.9 |
Average neutrophils (×109/L) | 13.9 ± 1.0 | 13.8 ± 0.9 | 0.9 |
Average absolute lymphocytes (×109/L) | 0.45 ± 0.04 | 0.89 ± 0.09 | <0.0001 |
Average red blood cells (×109/L) | 3.3 ± 0.1 | 3.2 ± 0.1 | 0.2 |
Average platelet count (per mm3) | 114 ± 9 | 153 ± 8 | 0.004 |
Average hemoglobin (g/L) | 10.3 ± 0.2 | 9.9 ± 0.2 | 0.2 |
Average sodium (mmol/L) | 136 ± 1 | 137 ± 1 | 0.6 |
Average potassium (mmol/L) | 4.2 ± 0.1 | 4.2 ± 0.1 | 0.7 |
Average chloride (mmol/L) | 101 ± 1 | 103 ± 1 | 0.05 |
Average CO2 (mmol/L) | 25 ± 1 | 24 ± 1 | 0.2 |
Average glucose (mmol/L) | 8.4 ± 0.4 | 8.7 ± 0.7 | 0.6 |
Average urea (mmol/L) | 16.2 ± 1.3 | 16.8 ± 1.2 | 0.7 |
Average ionized calcium (mmol/L) | 1.25 ± 0.21 | 1.16 ± 0.02 | 0.09 |
Average creatinine (mmol/L) | 143 ± 10 | 178 ± 21 | 0.1 |
Platelet units given | 8 ± 2 | 7 ± 4 | 0.9 |
Red blood cell units given | 9 ± 2 | 8 ± 3 | 0.8 |
Study drug induction volume (mL) | 5,934 ± 669 | 942 ± 152 | <0.0001 |
Methylprednisolone (mg) | 1,242 ± 278 | 495 ± 38 | <0.0001 |
Prednisone (mg) | 552 ± 38 | 626 ± 53 | 0.2 |
IV Mycophenolate Mofetil (mg) | 6,017 ± 788 | 6,000 ± 1005 | 1.0 |
p.o. Mycophenolate Mofetil (mg) | 14,983 ± 1025 | 16,317 ± 1145 | 0.4 |
Patients receiving cyclosporin A only | 12 | 11 | 1.0 |
Patients receiving tacrolimus only | 2 | 1 | 1.0 |
Patients converted from cyclosporin A to tacrolimus | 0 | 3 | 0.2 |
Patients converted from tacrolimus to cyclosporin A | 1 | 0 | 1.0 |
Cyclosporin A (mg) | 2,532 ± 348 | 2,621 ± 333 | 0.8 |
Tacrolimus (mg) | 40 ± 14 | 40 ± 6 | 1.0 |
Insulin (units) | 502 ± 80 | 724 ± 202 | 0.3 |
Total steroids for 1 year (mg) | 4,631 ± 638 | 3,846 ± 434 | 0.2 |