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Table 3 Postoperative laboratory data and drug administration

From: A randomized controlled trial of daclizumab versus anti-thymocyte globulin induction for heart transplantation

 

ATG (n = 15)

DZM (n = 15)

p value

Average white blood cells (×109/L)

16.6 ± 1.3

16.4 ± 1.2

0.9

Average neutrophils (×109/L)

13.9 ± 1.0

13.8 ± 0.9

0.9

Average absolute lymphocytes (×109/L)

0.45 ± 0.04

0.89 ± 0.09

<0.0001

Average red blood cells (×109/L)

3.3 ± 0.1

3.2 ± 0.1

0.2

Average platelet count (per mm3)

114 ± 9

153 ± 8

0.004

Average hemoglobin (g/L)

10.3 ± 0.2

9.9 ± 0.2

0.2

Average sodium (mmol/L)

136 ± 1

137 ± 1

0.6

Average potassium (mmol/L)

4.2 ± 0.1

4.2 ± 0.1

0.7

Average chloride (mmol/L)

101 ± 1

103 ± 1

0.05

Average CO2 (mmol/L)

25 ± 1

24 ± 1

0.2

Average glucose (mmol/L)

8.4 ± 0.4

8.7 ± 0.7

0.6

Average urea (mmol/L)

16.2 ± 1.3

16.8 ± 1.2

0.7

Average ionized calcium (mmol/L)

1.25 ± 0.21

1.16 ± 0.02

0.09

Average creatinine (mmol/L)

143 ± 10

178 ± 21

0.1

Platelet units given

8 ± 2

7 ± 4

0.9

Red blood cell units given

9 ± 2

8 ± 3

0.8

Study drug induction volume (mL)

5,934 ± 669

942 ± 152

<0.0001

Methylprednisolone (mg)

1,242 ± 278

495 ± 38

<0.0001

Prednisone (mg)

552 ± 38

626 ± 53

0.2

IV Mycophenolate Mofetil (mg)

6,017 ± 788

6,000 ± 1005

1.0

p.o. Mycophenolate Mofetil (mg)

14,983 ± 1025

16,317 ± 1145

0.4

Patients receiving cyclosporin A only

12

11

1.0

Patients receiving tacrolimus only

2

1

1.0

Patients converted from cyclosporin A to tacrolimus

0

3

0.2

Patients converted from tacrolimus to cyclosporin A

1

0

1.0

Cyclosporin A (mg)

2,532 ± 348

2,621 ± 333

0.8

Tacrolimus (mg)

40 ± 14

40 ± 6

1.0

Insulin (units)

502 ± 80

724 ± 202

0.3

Total steroids for 1 year (mg)

4,631 ± 638

3,846 ± 434

0.2