|
Average white blood cells (×109/L)
|
16.6 ± 1.3
|
16.4 ± 1.2
|
0.9
|
|
Average neutrophils (×109/L)
|
13.9 ± 1.0
|
13.8 ± 0.9
|
0.9
|
|
Average absolute lymphocytes (×109/L)
|
0.45 ± 0.04
|
0.89 ± 0.09
|
<0.0001
|
|
Average red blood cells (×109/L)
|
3.3 ± 0.1
|
3.2 ± 0.1
|
0.2
|
|
Average platelet count (per mm3)
|
114 ± 9
|
153 ± 8
|
0.004
|
|
Average hemoglobin (g/L)
|
10.3 ± 0.2
|
9.9 ± 0.2
|
0.2
|
|
Average sodium (mmol/L)
|
136 ± 1
|
137 ± 1
|
0.6
|
|
Average potassium (mmol/L)
|
4.2 ± 0.1
|
4.2 ± 0.1
|
0.7
|
|
Average chloride (mmol/L)
|
101 ± 1
|
103 ± 1
|
0.05
|
|
Average CO2 (mmol/L)
|
25 ± 1
|
24 ± 1
|
0.2
|
|
Average glucose (mmol/L)
|
8.4 ± 0.4
|
8.7 ± 0.7
|
0.6
|
|
Average urea (mmol/L)
|
16.2 ± 1.3
|
16.8 ± 1.2
|
0.7
|
|
Average ionized calcium (mmol/L)
|
1.25 ± 0.21
|
1.16 ± 0.02
|
0.09
|
|
Average creatinine (mmol/L)
|
143 ± 10
|
178 ± 21
|
0.1
|
|
Platelet units given
|
8 ± 2
|
7 ± 4
|
0.9
|
|
Red blood cell units given
|
9 ± 2
|
8 ± 3
|
0.8
|
|
Study drug induction volume (mL)
|
5,934 ± 669
|
942 ± 152
|
<0.0001
|
|
Methylprednisolone (mg)
|
1,242 ± 278
|
495 ± 38
|
<0.0001
|
|
Prednisone (mg)
|
552 ± 38
|
626 ± 53
|
0.2
|
|
IV Mycophenolate Mofetil (mg)
|
6,017 ± 788
|
6,000 ± 1005
|
1.0
|
|
p.o. Mycophenolate Mofetil (mg)
|
14,983 ± 1025
|
16,317 ± 1145
|
0.4
|
|
Patients receiving cyclosporin A only
|
12
|
11
|
1.0
|
|
Patients receiving tacrolimus only
|
2
|
1
|
1.0
|
|
Patients converted from cyclosporin A to tacrolimus
|
0
|
3
|
0.2
|
|
Patients converted from tacrolimus to cyclosporin A
|
1
|
0
|
1.0
|
|
Cyclosporin A (mg)
|
2,532 ± 348
|
2,621 ± 333
|
0.8
|
|
Tacrolimus (mg)
|
40 ± 14
|
40 ± 6
|
1.0
|
|
Insulin (units)
|
502 ± 80
|
724 ± 202
|
0.3
|
|
Total steroids for 1 year (mg)
|
4,631 ± 638
|
3,846 ± 434
|
0.2
|
