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Table 1 Monitoring procedures during abdominal normothermic oxygenated recirculation

From: Development of a preclinical model of donation after circulatory determination of death for translational application

Monitored parameters

Objectives

Type of monitoring

Corrective actions

Pump flow rate

2.5 to 3 l/min

Continuous monitoring

Vascular filling: saline and hydroxyethyl starch (10 ml/(kg h))

Mean arterial pressure

>60 mmHg

Continuous infusion of noradrenalin on the circuit

Central venous pressure

<5 mmHg

pH

7.5

Blood samples on the circuit every 30 minutes

Continuous infusion of sodium bicarbonate on the circuit

Partial pressure of carbon dioxide

30 to 40 mmHg

Sweeping gas flow adjustment

Partial pressure of oxygen

100 to 150 mmHg

Fraction of inspired oxygen adjustment

Activated clotting time

>200 s

 

Bolus of 5000 IU unfractionated heparin on the circuit