| |
Number of eventsa
|
Pre (n = 124)b
|
Post (n = 353)b
|
Hazard Ratio (95% CI)c
|
P value
|
|---|
|
BPAR
|
68 (19/49)
|
17.6%
|
15.5%
|
0.90 (0.50, 1.64)
|
0.73
|
|
Graft loss
|
29 (8/21)
|
8.6%
|
10.1%
|
1.04 (0.41, 2.61)
|
0.94
|
|
Death
|
26 (10/16)
|
9.8%
|
6.3%
|
0.54 (0.21, 1.39)
|
0.20
|
|
Composite
|
103 (29/74)
|
27.0%
|
25.7%
|
0.94 (0.58, 1.53)
|
0.81
|
- aTotal number of events (Pre group/Post group).
- bCumulative probability of the outcome at 5-years using the Kaplan-Meier product limit method.
- cPredictors in the Cox model include: timing of induction, indication (high risk recipient and donor, high immunologic risk recipient, high risk donor and low immunologic risk recipient), occurrence of DGF, weight-adjusted total rATG dose, recipient age, recipient sex, recipient race (Caucasian or non-Caucasian), cause of ESRD (diabetes or non-diabetes), time on dialysis, peak PRA, re-graft status, recipient BMI, donor age, donor sex, donor type (living or deceased), and transplant era (2002 to 2004, 2005 to 2007 and 2008 to 2009).
- BMI, body mass index; BPAR, biopsy-proven acute rejection; CI, confidence interval; DGF, delayed graft function; ESRD, end stage renal disease; PRA, panel reactive antibodies; rATG, rabbit antithymocyte globulin.
