| | Number of eventsa | Pre (n = 124)b | Post (n = 353)b | Hazard Ratio (95% CI)c | P value |
|---|
BPAR | 68 (19/49) | 17.6% | 15.5% | 0.90 (0.50, 1.64) | 0.73 |
Graft loss | 29 (8/21) | 8.6% | 10.1% | 1.04 (0.41, 2.61) | 0.94 |
Death | 26 (10/16) | 9.8% | 6.3% | 0.54 (0.21, 1.39) | 0.20 |
Composite | 103 (29/74) | 27.0% | 25.7% | 0.94 (0.58, 1.53) | 0.81 |
- aTotal number of events (Pre group/Post group).
- bCumulative probability of the outcome at 5-years using the Kaplan-Meier product limit method.
- cPredictors in the Cox model include: timing of induction, indication (high risk recipient and donor, high immunologic risk recipient, high risk donor and low immunologic risk recipient), occurrence of DGF, weight-adjusted total rATG dose, recipient age, recipient sex, recipient race (Caucasian or non-Caucasian), cause of ESRD (diabetes or non-diabetes), time on dialysis, peak PRA, re-graft status, recipient BMI, donor age, donor sex, donor type (living or deceased), and transplant era (2002 to 2004, 2005 to 2007 and 2008 to 2009).
- BMI, body mass index; BPAR, biopsy-proven acute rejection; CI, confidence interval; DGF, delayed graft function; ESRD, end stage renal disease; PRA, panel reactive antibodies; rATG, rabbit antithymocyte globulin.
