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Table 2 Clinical profiles of 133 donors and 133 recipients for living donor liver transplantation and comparison of their clinical profiles on day 1 (D1) and day 30 (D30) after transplantation

From: Biological interactions of CYP2C19 genotypes with CYP3A4*18, CYP3A5*3, and MDR1-3435 in living donor liver transplantation recipients

Category

Donor N = 133

Recipient N = 133

P value

Age (mean) (range)

30.27 (18 to 53)

42.62 (0.6-68)

<0.001

Sex M:F

83:50

98:35

0.292

  

D1

D30

D:RD1

D:RD30

RD 1:RD30

ALT

14.43 ± 14.75

252.35 ± 446.40

82.40 ± 244.43

<0.001

0.003

<0.001

AST

18.3 ± 7.19

292.42 ± 660.86

65.54 ± 300.20

<0.001

0.087

<0.001

T-Bil

0.64 ± 0.57

7.19 ± 11.71

1.24 ± 3.60

<0.001

0.071

<0.001

PT (INR)

0.97 ± 0.09

1.91 ± 3.34

1.05 ± 0.40

0.003

0.025

<0.001

Alb

4.24 ± 0.79

3.06 ± 0.88

3.74 ± 0.95

<0.001

0.148

<0.001

Tacrolimus (ng/mL) (n = 107)

2.51 ± 2.73

6.17 ± 9.58

  

<0.001

cyA (ng/mL) (n = 26)

283.89 ± 308.93

1058.30 ± 582.37

  

<0.001

  1. D, donor; D1, post liver transplantation day 1; D30, post liver transplantation day 30; R, recipient.