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Table 2 Clinical profiles of 133 donors and 133 recipients for living donor liver transplantation and comparison of their clinical profiles on day 1 (D1) and day 30 (D30) after transplantation

From: Biological interactions of CYP2C19 genotypes with CYP3A4*18, CYP3A5*3, and MDR1-3435 in living donor liver transplantation recipients

Category Donor N = 133 Recipient N = 133 P value
Age (mean) (range) 30.27 (18 to 53) 42.62 (0.6-68) <0.001
Sex M:F 83:50 98:35 0.292
   D1 D30 D:RD1 D:RD30 RD 1:RD30
ALT 14.43 ± 14.75 252.35 ± 446.40 82.40 ± 244.43 <0.001 0.003 <0.001
AST 18.3 ± 7.19 292.42 ± 660.86 65.54 ± 300.20 <0.001 0.087 <0.001
T-Bil 0.64 ± 0.57 7.19 ± 11.71 1.24 ± 3.60 <0.001 0.071 <0.001
PT (INR) 0.97 ± 0.09 1.91 ± 3.34 1.05 ± 0.40 0.003 0.025 <0.001
Alb 4.24 ± 0.79 3.06 ± 0.88 3.74 ± 0.95 <0.001 0.148 <0.001
Tacrolimus (ng/mL) (n = 107) 2.51 ± 2.73 6.17 ± 9.58    <0.001
cyA (ng/mL) (n = 26) 283.89 ± 308.93 1058.30 ± 582.37    <0.001
  1. D, donor; D1, post liver transplantation day 1; D30, post liver transplantation day 30; R, recipient.