Figure 4From: IL-13 signaling via IL-13Rα2 triggers TGF-β1-dependent allograft fibrosis Activation of a 'fibrotic program’ in allogeneically transplanted grafts. (A,B) PCR array using RNA extracted from explanted hearts (day 100) of allogeneically (FVB into DBA/1) or syngeneically (DBA/1 into DBA/1) transplanted mice demonstrated an upregulation of pro-fibrotic genes and a downregulation of anti-fibrotic genes in the allogeneic group.Back to article page