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Table 5 Logistic regression analysis: acute rejection episodes during the first 90 days after transplantation

From: Induction with interleukin-2 antagonist for transplantation of kidneys from older deceased donors: an observational study

 

Univariable

Multivariable

 

OR

95% CI

P

OR

95% CI

P

IL-2 minus

2.87

1.58 to 5.21

0.001

2.42

1.25 to 4.68

0.009

Any HLA-DR mismatch

1.98

1.09 to 3.60

0.03

2.32

1.19 to 4.52

0.01

Cold ischemia time (per hour)

0.90

0.84 to 0.96

0.001

0.90

0.84 to 0.97

0.003

Tacrolimus versus CsA

0.20

0.05 to 0.86

0.03

0.28

0.04 to 1.01

ns

CMV-positive recipient

0.46

0.24 to 0.90

0.02

0.62

0.30 to 1.30

ns

Time on dialysis (per year)

0.84

0.66 to 1.06

0.14

0.82

0.63 to 1.06

ns

Recipient age

1.00

0.98 to 1.02

0.88

0.98

0.95 to 1.01

ns

Recipient gender (male)

1.46

0.75 to 2.84

0.26

1.46

0.70 to 1.01

ns

  1. N=230; 63 rejection episodes, two patients excluded because of missing variables.
  2. The following variables were tested in the univariable model but not included in the multivariable model: CMV-positive donor, presence of HLA antibodies, donor gender, donor age, delayed graft function, any HLA-A or any HLA-B mismatch.