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Table 1 Transplantation characteristics and immunosuppressive treatment

From: Induction with interleukin-2 antagonist for transplantation of kidneys from older deceased donors: an observational study

  IL-2 plus IL-2 minus P
  (N=149) (N=83)  
Characteristics    
Recipient gender (male) 105 (71%) 59 (71%) ns
Recipient age (years); median (range) 64.5 (14.9 to 82.8) 65.8 (32.1 to 80.5) ns
Donor gender (male) 100 (67%) 38 (46%) 0.002
Donor age (years); median (range) 67.6 (60.2 to 89.0) 65.5 (60.3 to 78.8) 0.03
Time on dialysis (years); median (range) 1.5 (0.0 to 6.3) 1.4 (0.0 to 5.9) ns
Diabetic nephropathy 14 (9%) 8 (10%) ns
Vascular nephropathy 40 (27%) 32 (38%) ns
PRA positive recipients 10 (7%) 4 (5%) ns
Any HLA-A mismatch 122 (82%) 62 (75%) ns
Any HLA-B mismatch 130 (87%) 78 (94%) ns
Any HLA-DR mismatch 82 (55%) 41 (49%) ns
CMV-positive recipient 125 (84%) 57 (69%) 0.01
CMV-positive donor 121 (82%) 72 (87%) ns
Cold ischemia time (hours); mean ± SD 14.4 ± 5.1 13.3 ± 4.9 ns
Transplant year    
  2004 0 24  
  2005 6 26  
  2006 6 26  
  2007 43 6  
  2008 46 0  
  2009 48 1  
Initial CNI    
CsA 126 (85%) 80 (96%) 0.008
Tacrolimus 23 (15%) 3 (4%) 0.008
PRA, panel-reactive antibodies