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Table 3 Clinical studies with regulatory macrophages

From: Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs

Study

n

Source

Time

Total cell number

Cells/kg body weight

Ref.

KW

1

Donor spleen

+5

 

1.1 × 106

[56]

TAIC-I

12

Donor spleen

+5

0.9-5 × 108

1-7.5 × 106

[1]

FR

1

Donor blood

−17

4.8 × 109

6.9 × 107

[57]

TAIC-II

5

Donor blood

−5

1.4-5.9 × 109

1.7-10.4 × 107

[2]

M reg: MM, CA

2

Donor blood

−6/7

4.3-7.5 × 108

7-8 × 106

[3]