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Table 3 Clinical studies with regulatory macrophages

From: Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs

Study n Source Time Total cell number Cells/kg body weight Ref.
KW 1 Donor spleen +5   1.1 × 106 [56]
TAIC-I 12 Donor spleen +5 0.9-5 × 108 1-7.5 × 106 [1]
FR 1 Donor blood −17 4.8 × 109 6.9 × 107 [57]
TAIC-II 5 Donor blood −5 1.4-5.9 × 109 1.7-10.4 × 107 [2]
M reg: MM, CA 2 Donor blood −6/7 4.3-7.5 × 108 7-8 × 106 [3]