Table 2 Clinical translation of myeloid suppressor cell therapy in solid organ transplantation
| Origin | Time | Pre-clinical | Clinical | Ref. | |
|---|---|---|---|---|---|
| M reg | Donor | Pre- | Mouse, pig, dog | TAIC- I, TAIC-II, The ONE Study | [1–3, 6, 16, 56–58] |
| Tol-DC | Recipient | Peri-/post- | Rat, NHP | The ONE Study | [6, 18, 20, 53, 54] |
| DC-10 | Recipient/Donor DC10 + recipient Tr-1 | Peri-/post- | Rat | - | [59] |
| Rapa-DC | Donor-pulsed recipient | Pre-Post | Mouse | - | [25] |
| MDSC | Recipient | Peri-/Post- | Mouse | - | [60] |