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Table 2 Prolongation of allograft survival by RAPA-DC

From: Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation

Species

Graft

Source of DC

IS agent in vivo

Reference

Mouse

Heart

Bone marrow (BM) recipient-derived

None

10

   

FK506

10

   

RAPA

23

Rat

Limb

BM recipient-derived

ALS, CSA

18

Rat

Vascularized skin

BM recipient-derived

ALS, CSA

7

Mouse

Hematopoietic cells

Autologous BM-derived (unpulsed)

None

24

Mouse

Pancreatic islets

BM donor-derived

None

25

  1. ALS, anti-lymphocyte serum; CSA, cyclosporine A; IS, immunosuppression.