Transplant group A control ( n = 300, 84.5%) | Transplant group B cinacalcet ( n = 55, 15.5%) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Variable | Mean + SE | 95% CI | Range | Mean + SE | 95% CI | Range | p value | RR | 95% CI |
Dialysis vintage (years) | 6.33 ± 0.19 | 5.95–6.70 | 23.62 | 6.88 ± 0.32 | 6.24–7.53 | 11.06 | 0.0417 | - | - |
Age at time of RTx (years) | 53.67 ± 0.73 | 52.2–55.1 | 54.9 | 55.1 ± 1.3 | 52.6–57.6 | 33.7 | 0.5915 | - | - |
Creatinine (mg/dL) | 1.81 ± 0.04 | 1.73–1.90 | 4.80 | 1.64 ± 0.09 | 1.45–1.83 | 3.40 | 0.0589 | - | - |
Calcium (mmol/L) | 2.33 ± 0.01 | 2.30–2.35 | 1.42 | 2.42 ± 0.03 | 2.37–2.48 | 0.97 | 0.0045 | 1.2 | 1.1–1.4 |
Phosphate (mmol/L) | 1.06 ± 0.17 | 1.02–1.09 | 1.83 | 0.95 ± 0.04 | 0.87–1.03 | 2.02 | 0.0021 | 0.2 | 0.1–0.7 |
AP (U/L) | 83 ± 3 | 78–89 | 545 | 100 ± 6 | 78–101 | 262 | 0.0608 | - | - |
PTH 4 weeks post-transplant (pmol/L) | 20.3 ± 1.6 | 17.2–23.5 | 332 | 40.7 ± 4.0 | 32.8–48.7 | 135 | 0.0000 | 1.5 | 1.2–1.8 |
PTH on follow-up (pmol/L) | 18.4 ± 2.3 | 13.8–23.0 | 474.9 | 26.2 ± 2.3 | 21.6–30.8 | 72.4 | 0.0000a | - | - |
eGFR (CKD-EPI formula) | 44.4 ± 1.2 | 42.0–46.7 | 121.6 | 47.4 ± 2.6 | 42.1–52.6 | 86.3 | 0.2435 | - | - |
Follow-up after RTx (years) | 3.26 ± 0.12 | 3.03–3.48 | 8.08 | 3.50 ± 0.26 | 2.98–4.03 | 7.57 | 0.3641 | - | - |
Gender (%) | ♂ 60.3 | ♀ 39.7 | - | ♂ 50.9 | ♀ 49.1 | - | 0.2330 | - | - |
Parathyroidectomyb (%) | Yes 27.3 | No 72.7 | - | Yes 16.4 | No 83.6 | - | 0.0948 | - | - |
Cinacalcet use on waiting list (%) | Yes 14.3 | No 85.7 | - | Yes 45.5 | No 54.5 | - | 0.0000 | 5.0 | 2.7–9.3 |
Vitamin D use on waiting listb (%) | Yes 60.0 | No 40.0 | - | Yes 65.5 | No 35.5 | - | 0.5481 | - | - |
HPT pill burden on waiting listb | 0.72 ± 0.03 | 0.65–0.79 | 2 | 1.40 ± 0.08 | 1.24–1.56 | 2 | 0.0000 | 5.2 | 3.1–8.7 |