Figure 4From: Phospho-specific flow cytometry for pharmacodynamic monitoring of immunosuppressive therapy in transplantation(A) Example of the gating strategy used. CD4+ and CD8+ T cells were analyzed for their cell surface expression of CCR7 and CD45RO to define the naïve, effector memory (EM), central memory (CM) and effector memory RA + (EMRA) T-cell subsets. (B) Example of decreased IL-2-induced STAT5 phosphorylation after rATG therapy in CD8 central memory T cells (CD45RO + CCR7+) and not in CD4 central memory T cells.Back to article page