Figure 3From: Phospho-specific flow cytometry for pharmacodynamic monitoring of immunosuppressive therapy in transplantationSTAT5 phosphorylation by CD4+ T cells after whole blood activation with IL-2, IL-7 and IL-15 was inhibited in this patient on tofacitinib/CP-690,550 therapy. Cytokine-activated P-STAT5 is plotted at the Y-axis as the median fluorescence intensity (MFI) of cytokine-stimulated P-STAT5 minus the MFI of the unstimulated sample.Back to article page